Assay Detail
Functional
CHEMBL757419
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro anti-HIV activity in peripheral blood mononuclear cells.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis, anti-human immunodeficiency virus and anti-hepatitis B virus activities of novel oxaselenolane nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.28 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 7.16 |
| CHEMBL127637 | — | — | 1 | 6.29 |
| CHEMBL433859 | — | — | 1 | 6.06 |
| CHEMBL126870 | — | — | 1 | 5.62 |
| CHEMBL127096 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | EC50 | = | 70.0 | nM | 7.16 |
| CHEMBL127637 | — | EC50 | = | 510.0 | nM | 6.29 |
| CHEMBL433859 | — | EC50 | = | 880.0 | nM | 6.06 |
| CHEMBL126870 | — | EC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL127096 | — | EC50 | > | 10000.0 | nM | - |