Assay Detail
Binding
CHEMBL757701
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for the ability to displace Opioid receptor mu 1 specific radioligand [3H]DAGO
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Cyclic enkephalin analogues containing alpha-amino-beta-mercapto-beta,beta-pentamethylenepropionic acid at positions 2 or 5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.09 | 8.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8234 | ENKEPHALIN | — | 1 | 8.03 |
| CHEMBL3084309 | — | — | 1 | 7.84 |
| CHEMBL2370369 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8234 | ENKEPHALIN | Ki | = | 9.43 | nM | 8.03 |
| CHEMBL3084309 | — | Ki | = | 14.4 | nM | 7.84 |
| CHEMBL2370369 | — | Ki | = | 4010.0 | nM | 5.40 |