Assay Detail
Functional
CHEMBL758422
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Compound tested for cytotoxic Activity against P-388 cell line from mouse leukemia
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
On the mechanism of activation of designed enediynes with selective cytotoxicity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.88 | 7.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15924 | — | — | 1 | 7.01 |
| CHEMBL15907 | — | — | 1 | 5.80 |
| CHEMBL15828 | — | — | 1 | 5.80 |
| CHEMBL277573 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15924 | — | IC50 | = | 98.0 | nM | 7.01 |
| CHEMBL15907 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL15828 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL277573 | — | IC50 | = | 13000.0 | nM | 4.89 |