Assay Detail
Functional
CHEMBL761650
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro transcriptional activation of peroxisome proliferator activated alpha-receptor (PPAR) expressed in CV-1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL2128) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.20 | 4.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL683 | CLOFIBRIC ACID | 2.0 | 1 | 4.29 |
| CHEMBL346267 | — | — | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL683 | CLOFIBRIC ACID | EC50 | = | 51000.0 | nM | 4.29 |
| CHEMBL346267 | — | EC50 | = | 80000.0 | nM | 4.10 |