Compound Detail
CHEMBL346267
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Basic Information
| ChEMBL ID | CHEMBL346267 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RBSRTJKBLCCGPO-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
304.7
MW (Da)
4.18
ALogP
3
HBA
1
HBD
63.6
PSA (Ų)
0.81
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor alpha CHEMBL2128 | EC50 | 4.1 | 4.1 | 80000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor alpha | EC50 | = | 80000.0 | nM | 4.1 | In vitro transcriptional activation of peroxisome proliferator activated alpha-r... | 8576907 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8576907 | 10.1021/jm950395a | Peroxisome proliferator-activated receptor gamma | 2 |
| 8576907 | 10.1021/jm950395a | Peroxisome proliferator-activated receptor alpha | 1 |
| 8576907 | 10.1021/jm950395a | Peroxisome proliferator-activated receptor delta | 1 |
| 25050878 | 10.1016/j.ejmech.2014.07.056 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 1 |
Data from ChEMBL 36 via Core Engine