Assay Detail
Functional
CHEMBL761803
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the drug concentration that inhibited cell growth by 50% compared to un treated control cultures of Panc 02 cells
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Panc 02 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Intensely potent doxorubicin analogues: structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 7.71 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405105 | — | — | 1 | 10.00 |
| CHEMBL369851 | — | — | 1 | 9.52 |
| CHEMBL172785 | — | — | 1 | 9.22 |
| CHEMBL173260 | — | — | 1 | 7.85 |
| CHEMBL367998 | — | — | 1 | 7.22 |
| CHEMBL435344 | — | — | 1 | 7.17 |
| CHEMBL172827 | — | — | 1 | 7.10 |
| CHEMBL172683 | — | — | 1 | 7.02 |
| CHEMBL369872 | — | — | 1 | 7.00 |
| CHEMBL369364 | — | — | 1 | 6.96 |
| CHEMBL354402 | — | — | 1 | 6.85 |
| CHEMBL369873 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405105 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL369851 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL172785 | — | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL173260 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL367998 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL435344 | — | IC50 | = | 67.0 | nM | 7.17 |
| CHEMBL172827 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL172683 | — | IC50 | = | 95.0 | nM | 7.02 |
| CHEMBL369872 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL369364 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL354402 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL369873 | — | IC50 | = | 240.0 | nM | 6.62 |