Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL763451

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro inhibitory concentration against ram seminal vesicle prostaglandin G/H synthase 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Ovis aries
Tissue Seminal vesicle
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Prostaglandin G/H synthase 1 (CHEMBL2949)
Type SINGLE PROTEIN
Organism Ovis aries

Publication

Synthesis and evaluation of S-4-(3-thienyl)phenyl-alpha-methylacetic acid.
Mittal S, Malde A, Selvam C, Arun KH, Johar PS, Jachak SM, Ramarao P, Bharatam PV, Chawla HP.
Bioorg Med Chem Lett (2004) 14 : 979 -982
PubMed 15013005 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.65

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL175 DEXIBUPROFEN 4.0 1 5.65
CHEMBL2096754 1 4.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL175 DEXIBUPROFEN IC50 = 2260.0 nM 5.65
CHEMBL2096754 IC50 = 45240.0 nM 4.34