Assay Detail
Binding
CHEMBL765840
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding towards human progesterone receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.52 | 8.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65743 | — | — | 1 | 8.25 |
| CHEMBL418684 | — | — | 1 | 7.87 |
| CHEMBL303293 | — | — | 1 | 6.45 |
| CHEMBL66198 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65743 | — | Ki | = | 5.6 | nM | 8.25 |
| CHEMBL418684 | — | Ki | = | 13.5 | nM | 7.87 |
| CHEMBL303293 | — | Ki | = | 357.0 | nM | 6.45 |
| CHEMBL66198 | — | Ki | > | 1000.0 | nM | - |