Compound Detail
CHEMBL66198
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Basic Information
| ChEMBL ID | CHEMBL66198 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZWRSZEGSVDENRS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
435.2
MW (Da)
6.38
ALogP
2
HBA
1
HBD
21.3
PSA (Ų)
0.52
QED
1
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL208 | EC50 | 5.73 | 5.73 | 1871.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | EC50 | = | 1871.0 | nM | 5.73 | Effective concentration for antagonistic activity towards human progesterone in ... | 12781198 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12781198 | 10.1016/s0960-894x(03)00256-7 | Progesterone receptor | 7 |
Data from ChEMBL 36 via Core Engine