Assay Detail
Functional
CHEMBL767228
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition of Platelet activating factor (PAF) induced platelet aggregation in rabbit platelet rich plasma
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Syntheses and bioactivities of novel carbamates combining platelet activating factor (PAF) receptor antagonist with thromboxane synthase inhibitor (TxSI).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.08 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283815 | — | — | 1 | 7.39 |
| CHEMBL29639 | — | — | 1 | 7.33 |
| CHEMBL28642 | — | — | 1 | 6.86 |
| CHEMBL283814 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283815 | — | IC50 | = | 41.0 | nM | 7.39 |
| CHEMBL29639 | — | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL28642 | — | IC50 | = | 139.0 | nM | 6.86 |
| CHEMBL283814 | — | IC50 | = | 190.0 | nM | 6.72 |