Assay Detail
Functional
CHEMBL768004
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for antagonism of AII-induced contraction of rabbit aorta rings.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Conformationally restricted polysubstituted biphenyl derivatives with angiotensin II receptors antagonist properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.30 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274447 | — | — | 1 | 7.10 |
| CHEMBL311743 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274447 | — | Kd | = | 79.43 | nM | 7.10 |
| CHEMBL311743 | — | Kd | = | 3162.28 | nM | 5.50 |