Assay Detail
Functional
CHEMBL768008
Review assay metadata, readout intent, target linkage, and publication context from the same page.
pA2 value determined by their ability to block AngII induced contractile responses in rabbit aorta strips
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Chiral recognition of the angiotensin II (AT1) receptor by a highly potent phenoxyproline octanoamide
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL341716 | — | — | 1 | 7.00 |
| CHEMBL138918 | — | — | 1 | 7.00 |
| CHEMBL152168 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL341716 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL138918 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL152168 | — | Kd | = | 100.0 | nM | 7.00 |