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Assay Detail

CHEMBL768971

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro platelet aggregating activity in washed rabbit platelets
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Oryctolagus cuniculus
Confidence 1 — Organism
Curated By Intermediate

Target

Oryctolagus cuniculus (CHEMBL374)
Type ORGANISM
Organism Oryctolagus cuniculus

Publication

Structure-activity relationship in PAF-acether. 2. rac-1-O-Octadecyl-2-O-acetyl-3-O-[gamma-(dimethylamino)propyl]glycerol .
Heymans F, Borrel MC, Broquet C, Lefort J, Godfroid JJ.
J Med Chem (1985) 28 : 1094 -1096
PubMed 4020830 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 9.95 10.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1788194 1 10.24
CHEMBL12852 1 9.66
CHEMBL12428 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1788194 EC50 = 0.057 nM 10.24
CHEMBL12852 EC50 = 0.22 nM 9.66
CHEMBL12428 EC50 > 4000.0 nM -