Assay Detail
Functional
CHEMBL769231
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration of the drug against the antigen production against P3HR-1 strain of epstein barr virus-2 (EBV) in Raji cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Raji |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral activity of novel 5-(1-azido-2-haloethyl) and 5-(1-azido-, amino-, or methoxyethyl) analogs of 2'-deoxyuridine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.03 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 5.54 |
| CHEMBL3142421 | — | — | 1 | 5.40 |
| CHEMBL3142425 | — | — | 1 | 5.03 |
| CHEMBL3142423 | — | — | 1 | 4.96 |
| CHEMBL318153 | EDOXUDINE | 2.0 | 1 | 4.92 |
| CHEMBL3143951 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3142421 | — | EC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL3142425 | — | EC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL3142423 | — | EC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL318153 | EDOXUDINE | EC50 | = | 12100.0 | nM | 4.92 |
| CHEMBL3143951 | — | EC50 | = | 44600.0 | nM | 4.35 |