Assay Detail
Functional
CHEMBL770047
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for the ability to inhibit endothelin-1 (ET-1) induced arachidonic acid release in rabbit renal artery vascular smooth muscle cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
-Carbamate butenolide analogues as potent ETA selective endothelin receptor antagonists and prodrugs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8981 | PD-156707 | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8981 | PD-156707 | IC50 | = | 1.0 | nM | 9.00 |