Assay Detail
Functional
CHEMBL770364
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Bioactivity in vitro in rabbit jejunum (RJ) isolated organ preparation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Jejunum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.11 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL317956 | DELTORPHIN C | — | 1 | 6.29 |
| CHEMBL1790779 | — | — | 1 | 6.05 |
| CHEMBL2370328 | — | — | 1 | 6.00 |
| CHEMBL2370332 | — | — | 1 | - |
| CHEMBL2370331 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL317956 | DELTORPHIN C | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL1790779 | — | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL2370328 | — | IC50 | = | 995.0 | nM | 6.00 |
| CHEMBL2370332 | — | IC50 | > | 4000.0 | nM | - |
| CHEMBL2370331 | — | IC50 | > | 4000.0 | nM | - |