Assay Detail
Binding
CHEMBL772103
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Displacement of 3[H]PDBu from Protein kinase C gamma C1a domain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
The C4 hydroxyl group of phorbol esters is not necessary for protein kinase C binding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.41 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27768 | — | — | 1 | 8.54 |
| CHEMBL265998 | — | — | 1 | 8.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27768 | — | Ki | = | 2.91 | nM | 8.54 |
| CHEMBL265998 | — | Ki | = | 5.23 | nM | 8.28 |