Assay Detail
Binding
CHEMBL772111
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Displacement of [3H]- PDBu from Protein kinase C gamma C1b domain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.61 | 6.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27266 | INDOLACTUM | — | 1 | 6.67 |
| CHEMBL63262 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27266 | INDOLACTUM | Ki | = | 212.6 | nM | 6.67 |
| CHEMBL63262 | — | Ki | = | 288.1 | nM | 6.54 |