Assay Detail
Functional
CHEMBL772461
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the inhibition U-46619 (3 x10 E -8 M) induced platelet aggregation (TXA2 alpha receptor) in rabbit platelet rich plasma
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and pharmacology of 3-substituted sodium azulene-1-sulfonates and related compounds: non-prostanoid thromboxane A2 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.63 | 5.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL262655 | — | — | 1 | 5.06 |
| CHEMBL77223 | — | — | 1 | 4.19 |
| CHEMBL74674 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL262655 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL77223 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL74674 | — | IC50 | > | 100000.0 | nM | - |