Assay Detail
Functional
CHEMBL772468
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Concentration needed to inhibit PAF-induced platelet aggregation in rabbit PRP by 50%
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.85 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296958 | KADSURENONE | — | 1 | 5.48 |
| CHEMBL646 | TRIAZOLAM | 4.0 | 1 | 4.96 |
| CHEMBL295212 | — | — | 1 | 4.59 |
| CHEMBL661 | ALPRAZOLAM | 4.0 | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296958 | KADSURENONE | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL646 | TRIAZOLAM | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL295212 | — | IC50 | = | 25900.0 | nM | 4.59 |
| CHEMBL661 | ALPRAZOLAM | IC50 | = | 41200.0 | nM | 4.38 |