Assay Detail
Functional
CHEMBL772496
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In vivo antagonistic activity against collagen induced platelet aggregation (40 ug/mL)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity relationship in PAF-acether. 4. Synthesis and biological activities of carboxylate isosteres.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.07 | 4.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL133922 | — | — | 1 | 4.16 |
| CHEMBL335038 | — | — | 1 | 4.08 |
| CHEMBL295212 | — | — | 1 | 4.05 |
| CHEMBL422792 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL133922 | — | EC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL335038 | — | EC50 | = | 84000.0 | nM | 4.08 |
| CHEMBL295212 | — | EC50 | = | 89000.0 | nM | 4.05 |
| CHEMBL422792 | — | EC50 | = | 100000.0 | nM | 4.00 |