Assay Detail
Functional
CHEMBL772612
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of contraction of rabbit aorta strips measured as pA2 calculated by the method of Van Rossum
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
A new class of diacidic nonpeptide angiotensin II receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.84 | 8.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL436192 | — | — | 1 | 8.26 |
| CHEMBL340612 | — | — | 1 | 7.93 |
| CHEMBL132109 | — | — | 1 | 7.92 |
| CHEMBL128590 | — | — | 1 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL436192 | — | Kd | = | 5.495 | nM | 8.26 |
| CHEMBL340612 | — | Kd | = | 11.75 | nM | 7.93 |
| CHEMBL132109 | — | Kd | = | 12.02 | nM | 7.92 |
| CHEMBL128590 | — | Kd | = | 57.54 | nM | 7.24 |