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Assay Detail

CHEMBL774998

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration required for antithrombotic efficacy in rabbit arterio-venous shunt model
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Oryctolagus cuniculus
Confidence 1 — Organism
Curated By Intermediate

Target

Oryctolagus cuniculus (CHEMBL374)
Type ORGANISM
Organism Oryctolagus cuniculus

Publication

Nonbenzamidine isoxazoline derivatives as factor Xa inhibitors.
Quan ML, Ellis CD, He MY, Liauw AY, Lam PY, Rossi KA, Knabb RM, Luettgen JM, Wright MR, Wong PC, Wexler RR.
Bioorg Med Chem Lett (2003) 13 : 1023 -1028
PubMed 12643903 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.26 8.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL267438 1 8.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL267438 Ki = 5.5 nM 8.26