Assay Detail
Binding
CHEMBL801233
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for binding affinity against sigma 1 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sigma non-opioid intracellular receptor 1 (CHEMBL287) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structural features important for sigma 1 receptor binding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.08 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL60542 | (+)-PENTAZOCINE | — | 1 | 8.77 |
| CHEMBL282433 | DITOLYLGUANIDINE | — | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL60542 | (+)-PENTAZOCINE | Ki | = | 1.7 | nM | 8.77 |
| CHEMBL282433 | DITOLYLGUANIDINE | Ki | = | 41.0 | nM | 7.39 |