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Assay Detail

CHEMBL806128

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Candida albicans Squalene Epoxidase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Candida albicans
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Squalene monooxygenase (CHEMBL3592)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Squalene analogues containing isopropylidene mimics as potential inhibitors of pig liver squalene epoxidase and oxidosqualene cyclase.
Sen SE, Prestwich GD.
J Med Chem (1989) 32 : 2152 -2158
PubMed 2769687 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL822 TERBINAFINE 4.0 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL822 TERBINAFINE Ki = 30.0 nM 7.52