Assay Detail
Binding
CHEMBL806132
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Binding affinity of the radio labeled [3H]5-Methyl-6-nitroquipazine compound against Serotonin transporter in rat frontal cortex homogenates
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Frontal cortex |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent serotonin transporter (CHEMBL313) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 10.29 | 10.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41140 | 6-NITROQUIPAZINE | — | 1 | 10.29 |
| CHEMBL121952 | — | — | 1 | 10.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41140 | 6-NITROQUIPAZINE | Kd | = | 0.051 | nM | 10.29 |
| CHEMBL121952 | — | Kd | = | 0.051 | nM | 10.29 |