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Assay Detail

CHEMBL806213

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Serotonin (5-HT) reuptake using cloned human transporter was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Sodium-dependent serotonin transporter (CHEMBL228)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2002 Medicinal Chemistry Division Award address: monoamine transporters and opioid receptors. Targets for addiction therapy.
Carroll FI.
J Med Chem (2003) 46 : 1775 -1794
PubMed 12723940 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL50858 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL50858 IC50 = 1.0 nM 9.00