Assay Detail
Binding
CHEMBL806668
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Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D220V by compound was evaluated
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (CHEMBL4438) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.55 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL280487 | OKADAIC ACID | — | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL280487 | OKADAIC ACID | IC50 | = | 28.0 | nM | 7.55 |