Assay Detail
Binding
CHEMBL808198
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for binding affinity against sigma receptor using DTG as radioligand
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sigma non-opioid intracellular receptor 1 (CHEMBL287) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.97 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45491 | — | — | 2 | 6.26 |
| CHEMBL300647 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45491 | — | Ki | = | 550.0 | nM | 6.26 |
| CHEMBL45491 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL300647 | — | Ki | = | 1600.0 | nM | 5.80 |