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Assay Detail

CHEMBL808869

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Functional
Compound was tested for its ability to inhibit the uptake of Serotonin in Serotonin transporter system
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Sodium-dependent serotonin transporter (CHEMBL228)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons.
Zimmermann K, Hengerer B.
Bioorg Med Chem Lett (1998) 8 : 261 -266
PubMed 9871666 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.54 6.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL26320 1 6.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL26320 IC50 = 289.0 nM 6.54