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Assay Detail

CHEMBL811366

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Functional
Ctotoxic related antitumor activity against human cancer cell lines T-47 D
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type T47D
Confidence 1 — Organism
Curated By Intermediate

Target

T47D (CHEMBL614361)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and characterization of the antitumor activities of analogues of meridine, a marine pyridoacridine alkaloid.
Delfourne E, Darro F, Bontemps-Subielos N, Decaestecker C, Bastide J, Frydman A, Kiss R.
J Med Chem (2001) 44 : 3275 -3282
PubMed 11563926 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.58 5.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL424062 1 5.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL424062 IC50 = 2600.0 nM 5.58