Assay Detail
Functional
CHEMBL812094
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro antiparasitic activity against Trypanosoma cruzi (epimastigotes)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39581 | — | — | 1 | 5.66 |
| CHEMBL110971 | — | — | 1 | - |
| CHEMBL54004 | — | — | 1 | - |
| CHEMBL299988 | — | — | 1 | - |
| CHEMBL52761 | — | — | 1 | - |
| CHEMBL55264 | — | — | 1 | - |
| CHEMBL298547 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39581 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL110971 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL54004 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL299988 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL52761 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL55264 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL298547 | — | IC50 | > | 70000.0 | nM | - |