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Assay Detail

CHEMBL812104

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against Trypanosoma cruzi trypomastigotes
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Confidence 1 — Organism
Curated By Intermediate

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

Synthesis of polyamine derivatives for the preparation of affinity chromatography columns for the search of new Trypanosoma cruzi targets.
Davioud-Charvet E, Berecibar A, Girault S, Landry V, Drobecq H, Sergheraert C.
Bioorg Med Chem Lett (1999) 9 : 1567 -1572
PubMed 10386937 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL290270 1 5.30
CHEMBL41307 1 5.30
CHEMBL405454 1 5.30
CHEMBL38733 1 5.30
CHEMBL41106 1 5.30
CHEMBL39045 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL290270 IC50 = 5000.0 nM 5.30
CHEMBL41307 IC50 = 5000.0 nM 5.30
CHEMBL405454 IC50 = 5000.0 nM 5.30
CHEMBL38733 IC50 = 5000.0 nM 5.30
CHEMBL41106 IC50 = 5000.0 nM 5.30
CHEMBL39045 IC50 = 5000.0 nM 5.30