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Assay Detail

CHEMBL812552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for its inhibitory activity against the Serotonin transporter
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Sodium-dependent serotonin transporter (CHEMBL228)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Indoline and piperazine containing derivatives as a novel class of mixed D(2)/D(4) receptor antagonists. Part 2: asymmetric synthesis and biological evaluation.
Zhao H, He X, Thurkauf A, Hoffman D, Kieltyka A, Brodbeck R, Primus R, Wasley JW.
Bioorg Med Chem Lett (2002) 12 : 3111 -3115
PubMed 12372513 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.27 6.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL320597 1 6.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL320597 Ki = 532.0 nM 6.27