Assay Detail
Functional
CHEMBL812898
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Compound was evaluated for growth brucei LAB 110 strain.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structural comparison of alkylpolyamine analogues with potent in vitro antitumor or antiparasitic activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.50 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93014 | — | — | 1 | 6.90 |
| CHEMBL93314 | — | — | 1 | 4.84 |
| CHEMBL93088 | — | — | 1 | 4.75 |
| CHEMBL96761 | — | — | 1 | - |
| CHEMBL92122 | — | — | 1 | - |
| CHEMBL92123 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93014 | — | IC50 | = | 125.0 | nM | 6.90 |
| CHEMBL93314 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL93088 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL96761 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL92122 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL92123 | — | IC50 | > | 100000.0 | nM | - |