Assay Detail
Binding
CHEMBL813408
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the inhibition of subtilisin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Proprotein convertase subtilisin/kexin type 9 (CHEMBL2929) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Diphenylborinic acid is a strong inhibitor of serine proteases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.26 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31523 | PHENYL BUTYL BORINIC ACID | — | 1 | 6.00 |
| CHEMBL81556 | DIPHENYL BORINIC ACID | — | 1 | 4.52 |
| CHEMBL21485 | PHENYLBORONIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31523 | PHENYL BUTYL BORINIC ACID | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL81556 | DIPHENYL BORINIC ACID | Ki | = | 30000.0 | nM | 4.52 |
| CHEMBL21485 | PHENYLBORONIC ACID | Ki | = | 470000.0 | nM | - |