Compound Detail
CHEMBL31523
PHENYL BUTYL BORINIC ACID Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL31523 |
| Name | PHENYL BUTYL BORINIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QZBRLXORJDJXAL-UHFFFAOYSA-N |
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
162.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proprotein convertase subtilisin/kexin type 9 CHEMBL2929 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 5.96 | 5.96 | 1100.0 | 1 |
| Chymotrypsinogen A CHEMBL3314 | Ki | 5.1 | 5.095 | 8000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proprotein convertase subtilisin/kexin type 9 | Ki | = | 1000.0 | nM | 6.0 | Compound was tested for the inhibition of subtilisin | - |
| Unchecked | Ki | = | 1100.0 | nM | 5.96 | Inhibition constant against subtilisin Carlsberg enzyme | - |
| Chymotrypsinogen A | Ki | = | 8000.0 | nM | 5.1 | Compound was tested for the inhibition of chymotrypsin | - |
| Chymotrypsinogen A | Ki | = | 8100.0 | nM | 5.09 | Inhibition constant against Chymotrypsinogen | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80401-7 | Chymotrypsinogen A | 1 |
| - | 10.1016/S0960-894X(01)80401-7 | Proprotein convertase subtilisin/kexin type 9 | 1 |
| - | 10.1016/S0960-894X(00)80519-3 | Unchecked | 1 |
| - | 10.1016/S0960-894X(00)80519-3 | Chymotrypsinogen A | 1 |
Data from ChEMBL 36 via Core Engine