Assay Detail
Binding
CHEMBL661237
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Compound was tested for the inhibition of chymotrypsin
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Diphenylborinic acid is a strong inhibitor of serine proteases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.77 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31523 | PHENYL BUTYL BORINIC ACID | — | 1 | 5.10 |
| CHEMBL81556 | DIPHENYL BORINIC ACID | — | 1 | 4.70 |
| CHEMBL78562 | PHENYL METHYL BORINIC ACID | — | 1 | 4.52 |
| CHEMBL21485 | PHENYLBORONIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31523 | PHENYL BUTYL BORINIC ACID | Ki | = | 8000.0 | nM | 5.10 |
| CHEMBL81556 | DIPHENYL BORINIC ACID | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL78562 | PHENYL METHYL BORINIC ACID | Ki | = | 30000.0 | nM | 4.52 |
| CHEMBL21485 | PHENYLBORONIC ACID | Ki | = | 640000.0 | nM | - |