Assay Detail
Functional
CHEMBL814987
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Effect on proliferation of human brain tumor (glioblastoma) cell line U373 by MTT assay method
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-373MG ATCC |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anticancer activity of synthetic analogues of the phorboxazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.76 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217666 | — | — | 1 | 8.17 |
| CHEMBL217667 | — | — | 1 | 7.56 |
| CHEMBL265005 | — | — | 1 | 7.54 |
| CHEMBL17461 | — | — | 1 | - |
| CHEMBL262841 | — | — | 1 | - |
| CHEMBL278228 | — | — | 1 | - |
| CHEMBL15275 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217666 | — | IC50 | = | 6.7 | nM | 8.17 |
| CHEMBL217667 | — | IC50 | = | 27.4 | nM | 7.56 |
| CHEMBL265005 | — | IC50 | = | 29.2 | nM | 7.54 |
| CHEMBL17461 | — | IC50 | > | 2000.0 | nM | - |
| CHEMBL262841 | — | IC50 | > | 2000.0 | nM | - |
| CHEMBL278228 | — | IC50 | > | 2000.0 | nM | - |
| CHEMBL15275 | — | IC50 | > | 2000.0 | nM | - |