Assay Detail
Binding
CHEMBL816560
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Inhibitory activity against Thrombin.
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design of benzamidine-type inhibitors of factor Xa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 4.96 | 6.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137311 | — | — | 1 | 6.35 |
| CHEMBL423699 | — | — | 1 | 5.41 |
| CHEMBL135198 | — | — | 1 | 4.96 |
| CHEMBL135998 | — | — | 1 | 4.82 |
| CHEMBL336844 | — | — | 1 | 4.82 |
| CHEMBL137780 | — | — | 1 | 4.60 |
| CHEMBL135815 | — | — | 1 | 4.39 |
| CHEMBL135041 | — | — | 1 | 4.34 |
| CHEMBL133027 | — | — | 1 | - |
| CHEMBL341933 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137311 | — | Ki | = | 450.0 | nM | 6.35 |
| CHEMBL423699 | — | Ki | = | 3900.0 | nM | 5.41 |
| CHEMBL135198 | — | Ki | = | 11000.0 | nM | 4.96 |
| CHEMBL135998 | — | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL336844 | — | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL137780 | — | Ki | = | 25000.0 | nM | 4.60 |
| CHEMBL135815 | — | Ki | = | 41000.0 | nM | 4.39 |
| CHEMBL135041 | — | Ki | = | 46000.0 | nM | 4.34 |
| CHEMBL133027 | — | Ki | > | 1000000.0 | nM | - |
| CHEMBL341933 | — | Ki | > | 1000000.0 | nM | - |