Assay Detail
Binding
CHEMBL816563
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against thrombin.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.31 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL104731 | — | — | 1 | 8.60 |
| CHEMBL1166 | ARGATROBAN | 4.0 | 1 | 8.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL104731 | — | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL1166 | ARGATROBAN | Ki | = | 9.6 | nM | 8.02 |