Assay Detail
Functional
CHEMBL821657
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The compound was evaluated in vitro for the inhibition of murine leukemia P388D1 cell proliferation.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological properties of 1069C: a new synthetic antitumour agent with very low cross-resistance potential
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.59 | 9.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 9.21 |
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 8.77 |
| CHEMBL90555 | VINCRISTINE | 4.0 | 1 | 8.33 |
| CHEMBL418565 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | IC50 | = | 0.62 | nM | 9.21 |
| CHEMBL159 | VINBLASTINE | IC50 | = | 1.7 | nM | 8.77 |
| CHEMBL90555 | VINCRISTINE | IC50 | = | 4.7 | nM | 8.33 |
| CHEMBL418565 | — | IC50 | = | 8.9 | nM | 8.05 |