Assay Detail
Functional
CHEMBL822660
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ADP-induced platelet aggregation of human PRP in the presence of pig aortal microsomes (PAM)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.67 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283656 | DAZMEGREL | 2.0 | 1 | 5.70 |
| CHEMBL537708 | DAZOXIBEN HYDROCHLORIDE | -1.0 | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283656 | DAZMEGREL | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL537708 | DAZOXIBEN HYDROCHLORIDE | IC50 | = | 2280.0 | nM | 5.64 |