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Assay Detail

CHEMBL823403

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Functional
Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma (PRP)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Oryctolagus cuniculus
Tissue Plasma
Confidence 1 — Organism
Curated By Expert

Target

Oryctolagus cuniculus (CHEMBL374)
Type ORGANISM
Organism Oryctolagus cuniculus

Publication

Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.
Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E.
J Med Chem (1992) 35 : 2672 -2687
PubMed 1321910 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.32 5.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL90958 1 5.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL90958 EC50 = 4770.0 nM 5.32