Assay Detail
Functional
CHEMBL824577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration in ZR-75-1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ZR-75-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.69 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51483 | GOSSYPOL | 3.0 | 1 | 5.08 |
| CHEMBL135650 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51483 | GOSSYPOL | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL135650 | — | IC50 | = | 50000.0 | nM | 4.30 |