Assay Detail
Binding
CHEMBL829041
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]-Ang II from pig uterus myometrium angiotensin II type 2 (AT2) receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
AT2-selective angiotensin II analogues containing tyrosine-functionalized 5,5-bicyclic thiazabicycloalkane dipeptide mimetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.78 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL187880 | — | — | 1 | 9.00 |
| CHEMBL408403 | ANGIOTENSIN II | 4.0 | 1 | 8.92 |
| CHEMBL268815 | — | — | 1 | 8.85 |
| CHEMBL216331 | — | — | 1 | 8.68 |
| CHEMBL190286 | — | — | 1 | 8.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL187880 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL408403 | ANGIOTENSIN II | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL268815 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL216331 | — | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL190286 | — | Ki | = | 3.7 | nM | 8.43 |