Assay Detail
Binding
CHEMBL829385
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against butyrylcholinesterase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.49 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95 | TACRINE | 4.0 | 1 | 7.57 |
| CHEMBL195418 | — | — | 1 | 7.50 |
| CHEMBL195241 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95 | TACRINE | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL195418 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL195241 | — | IC50 | = | 40.0 | nM | 7.40 |