Assay Detail
Binding
CHEMBL832951
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Irreversible inhibition of fatty acid amide hydrolase
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.43 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL112486 | — | — | 1 | 10.00 |
| CHEMBL97038 | DODECANESULFONYL FLUORIDE | — | 1 | 8.52 |
| CHEMBL113263 | METHYL DODECYLPHOSPHONOFLUORIDOATE | — | 1 | 8.52 |
| CHEMBL191481 | OCTADECANESULFONYL FLUORIDE | — | 1 | 8.40 |
| CHEMBL6206 | BROMOENOL LACTONE | — | 1 | 6.10 |
| CHEMBL347894 | — | — | 1 | 5.58 |
| CHEMBL190503 | PHENYLMETHYLSULFONYLFLUORIDE | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL112486 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL97038 | DODECANESULFONYL FLUORIDE | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL113263 | METHYL DODECYLPHOSPHONOFLUORIDOATE | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL191481 | OCTADECANESULFONYL FLUORIDE | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL6206 | BROMOENOL LACTONE | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL347894 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL190503 | PHENYLMETHYLSULFONYLFLUORIDE | IC50 | = | 13000.0 | nM | 4.89 |