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Compound Detail

CHEMBL113263

METHYL DODECYLPHOSPHONOFLUORIDOATE
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CCCCCCCCCCCCP(=O)(F)OC

Basic Information

ChEMBL ID CHEMBL113263
Name METHYL DODECYLPHOSPHONOFLUORIDOATE
Phase Preclinical
Structure Type MOL
InChI Key AUDRDSJPHLTEGD-UHFFFAOYSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

266.3
MW (Da)
5.72
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.33
QED
1
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C13H28FO2P
MW 266.34
Aromatic Rings 0
Heavy Atoms 17
NP-Likeness 0.10

Activity Summary

IC50 3 meas. best 8.7

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Fatty-acid amide hydrolase 1
CHEMBL3455
IC50 8.7 8.7 2.0 1
Fatty-acid amide hydrolase 1
CHEMBL2243
IC50 8.52 8.52 3.0 1
Fatty-acid amide hydrolase 1
CHEMBL3229
IC50 8.52 8.52 3.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
12951114 10.1016/s0960-894x(03)00721-2 Fatty-acid amide hydrolase 1 2
16078824 10.1021/jm058183t Fatty-acid amide hydrolase 1 1

Data from ChEMBL 36 via Core Engine