Assay Detail
Functional
CHEMBL833926
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potency towards T47D cell
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.90 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL360771 | — | — | 1 | 6.90 |
| CHEMBL368448 | — | — | 1 | - |
| CHEMBL362489 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL360771 | — | IC50 | = | 125.0 | nM | 6.90 |
| CHEMBL368448 | — | IC50 | < | 100.0 | nM | - |
| CHEMBL362489 | — | IC50 | 250.0 | nM | - |